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Lowest Fare Flights from Panama with Spirit Airlines

Trending Destinations from Panama

*Fares presented below are available at the beginning of each day, but may sell out. Additional baggage fees and fees for other services may apply. Other terms and conditions may apply.

  1. PTY-FLL

    Panama City to Fort Lauderdale

    Departing 08/29/2018

    Fares From
    $152*

    One-way

  2. PTY-MCO

    Panama City to Orlando

    Departing 08/23/2018

    Fares From
    $205*

    One-way

  3. PTY-ATL

    Panama City to Atlanta

    Departing 08/23/2018

    Fares From
    $209*

    One-way

  4. PTY-LGA

    Panama City to New York

    Departing 08/29/2018

    Fares From
    $333*

    One-way

  5. PTY-LAX

    Panama City to Los Angeles

    Departing 08/28/2018

    Fares From
    $257*

    One-way

  6. PTY-BWI

    Panama City to Baltimore

    Departing 08/26/2018

    Fares From
    $397*

    One-way

*Fares presented below are available at the beginning of each day, but may sell out. Additional baggage fees and fees for other services may apply. Other terms and conditions may apply.

  1. Panama City (PTY) to Fort Lauderdale (FLL)

    One-way

    Departing 09/22/2018

    Fares From
    $147*
  2. Panama City (PTY) to Orlando (MCO)

    One-way

    Departing 11/14/2018

    Fares From
    $179*
  3. Panama City (PTY) to Atlanta (ATL)

    One-way

    Departing 10/01/2018

    Fares From
    $205*
  4. Panama City (PTY) to New York (LGA)

    One-way

    Departing 09/18/2018

    Fares From
    $215*
  5. Panama City (PTY) to Baltimore (BWI)

    One-way

    Departing 09/23/2018

    Fares From
    $205*
  6. Panama City (PTY) to Los Angeles (LAX)

    One-way

    Departing 09/29/2018

    Fares From
    $219*
  7. Panama City (PTY) to New York/Newark (EWR)

    One-way

    Departing 11/14/2018

    Fares From
    $208*
  8. Panama City (PTY) to Chicago (ORD)

    One-way

    Departing 09/19/2018

    Fares From
    $167*
  9. Panama City (PTY) to Las Vegas (LAS)

    One-way

    Departing 10/01/2018

    Fares From
    $242*
  10. Panama City (PTY) to Houston (IAH)

    One-way

    Departing 11/01/2018

    Fares From
    $247*
Lowest Fare Flights from Panama with Spirit Airlines

Travelling from Panama

Spirit Airlines is the perfect travel partner for affordable flights from Panama. Fly to over 60 destinations across the U.S., or hop to 15 destinations around the Caribbean and Latin America.

Flying from Panama

Ready to create some memories, but travel costs holding you back? We feel you! Take the pressure off by flying with Spirit Airlines from Panama City (PTY). Start with our Bare Fare™ pricing and only pay for the items you’ll actually use – not someone else’s “free” bags!

Enroll in FREE SPIRITTM, our frequent flyer program, to bank miles from your Panama flights – and every time you fly with Spirit Airlines!