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Lowest Fare Flights from Panama with Spirit Airlines

Trending Destinations from Panama

*Fares presented below are available at the beginning of each day, but may sell out. Additional baggage fees and fees for other services may apply. Other terms and conditions may apply.

  1. PTY-FLL

    Panama City to Fort Lauderdale

    Departing 02/04/2019

    Fares From
    $126*

    One Way

  2. PTY-MCO

    Panama City to Orlando

    Departing 02/04/2019

    Fares From
    $131*

    One Way

  3. PTY-LGA

    Panama City to New York

    Departing 02/02/2019

    Fares From
    $175*

    One Way

  4. PTY-ATL

    Panama City to Atlanta

    Departing 01/26/2019

    Fares From
    $174*

    One Way

  5. PTY-DFW

    Panama City to Dallas

    Departing 02/02/2019

    Fares From
    $184*

    One Way

  6. PTY-BOS

    Panama City to Boston

    Departing 02/04/2019

    Fares From
    $179*

    One Way

Low Airfares from Panama

*Fares presented below are available at the beginning of each day, but may sell out. Additional baggage fees and fees for other services may apply. Other terms and conditions may apply.

  1. Panama City (PTY) to Fort Lauderdale (FLL)

    One Way

    Departing 08/17/2019

    Fares From
    $372*
  2. Panama City (PTY) to Orlando (MCO)

    One Way

    Departing 05/31/2019

    Fares From
    $336*
  3. Panama City (PTY) to New York (LGA)

    One Way

    Departing 03/02/2019

    Fares From
    $254*
  4. Panama City (PTY) to Atlanta (ATL)

    One Way

    Departing 02/09/2019

    Fares From
    $174*
  5. Panama City (PTY) to Dallas (DFW)

    One Way

    Departing 05/13/2019

    Fares From
    $211*
  6. Panama City (PTY) to Boston (BOS)

    One Way

    Departing 04/21/2019

    Fares From
    $402*
  7. Panama City (PTY) to New York/Newark (EWR)

    One Way

    Departing 05/15/2019

    Fares From
    $198*
  8. Panama City (PTY) to Chicago (ORD)

    One Way

    Departing 02/08/2019

    Fares From
    $188*
  9. Panama City (PTY) to Tampa (TPA)

    One Way

    Departing 03/04/2019

    Fares From
    $174*
  10. Panama City (PTY) to Saint Croix (STX)

    One Way

    Departing 05/19/2019

    Fares From
    $261*
Lowest Fare Flights from Panama with Spirit Airlines

Travelling from Panama

Spirit Airlines is the perfect travel partner for affordable flights from Panama. Fly to over 60 destinations across the U.S., or hop to 15 destinations around the Caribbean and Latin America.

Flying from Panama

Ready to create some memories, but travel costs holding you back? We feel you! Take the pressure off by flying with Spirit Airlines from Panama City (PTY). Start with our Bare Fare™ pricing and only pay for the items you’ll actually use – not someone else’s “free” bags!

Enroll in FREE SPIRITTM, our frequent flyer program, to bank miles from your Panama flights – and every time you fly with Spirit Airlines!